ea0041gp200 | Thyroid - Translational & Clinical | ECE2016
Poplawska-Kita Anna
, Siewko Katarzyna
, Kosciuszko-Zdrodowska Maria
, Lipinska Danuta
, Milewski Robert
, Poplawski Lukasz
, Szelachowska Malgorzata
, Gorska Maria
Aim: Clinical studies in Hashimoto thyroditis (HT) confirm, that even a minor thyroid dysfunction is related to significant changes in body mass. Betatrophin, also known as TD26/RIFL/lipasin/ANGPTL8/C19orf80, is a novel protein predominantly expressed in human liver and adipose tissue. Stimulators of betatrophin, such as thyroid hormones are usually relevant to energy expenditure or thermogenesis. The mechanisms of action of betatrophin are still unknown. In the present study ...